Technology Licensing Opportunities

1. Laboratories in and affiliated with the Department are engaged in state of the art research studying bacteria, fungi, parasites, viruses, and host defenses:
   

   • Bordetella pertussis, E. coli, Haemophilus, Helicobacter pylori, Neisseria, Rhodobacter, Streptococci, Salmonella

   • Histoplasma

   • Ascaris, Entamoeba, filarial nematodes, Leishmania, malaria, Plasmodium, Toxoplasma

   • cytomegaloviruses, Epstein Barr virus, hepatitis C virus, herpes viruses, HIV, HTLV, Sindbis virus, varicella zoster virus, yellow fever virus

2. Highlights of recent technology licensing include:

   • Sindbis virus gene expression vectors.
     Kits now marketed by Invitrogen

   • Genetically Engineered Cell Line For Detecting Herpes Simplex Virus.
     An exclusive license agreement for developing diagnostic kits based on this patented technology has been signed with DHI, and FDA approval for a first generation kit was received 5/1/95.

   • Hepatitis C genomic clones.

3. Examples of other technologies available for licensing:

   • Vectors for analysis of gene expression in gram positive bacteria.

   • A transposon for shuttle mutagenesis of the genomes of gram positive bacteria.

   • E. coli strain overproducing for RNase I and RNase I*.

   • Composition and Method for Distinguishing Virulent and Non-virulent Toxoplasma Infections.

4. There are several ways to find items of interest:

   1. Browse the Technology developed by individual research groups.

   2. Search or browse the Research Collaboration Opportunities book compiled by the Washington University School of Medicine

   3. Contact: Technology Management Program

      Campus Box 8013 Washington University 660 South Euclid Avenue St. Louis, MO 63110

      Phone: 314-747-0920 FAX: 314-362-5872 email: gonosm@medicine.wustl.edu